2024
Sasoni N, Caracciolo B, Cabeza MS, Gamarra S, Carnovale S, Garcia-Effron G. Antifungal susceptibility testing following the CLSI M27 document, along with the measurement of MFC/MIC ratio, could be the optimal approach to detect amphotericin B resistance in Clavispora (Candida) lusitaniae. Susceptibility patterns of contemporary isolates of this species. Antimicrob Agents Chemother. 2024 Jan 10;68(1):e0096823. doi: 10.1128/aac.00968-23.
2023
Garcia-Effron G. The rising threat of intrinsically resistant Candida species in Argentina. Rev Argent Microbiol. 2023 Jul-Sep;55(3):201-203. doi: 10.1016/j.ram.2023.09.001.
Brito Devoto T, Hermida-Alva K, Posse G, Finquelievich JL, García-Effrón G, Cuestas ML. Antifungal susceptibility patterns for Aspergillus, Scedosporium, and Exophiala isolates recovered from cystic fibrosis patients against amphotericin B, and three triazoles and their impact after long-term therapies. Med Mycol. 2023 Aug 2;61(8):myad089. doi: 10.1093/mmy/myad089.PMID: 37591630
Giusiano G, Tracogna F, Santiso G, Rojas F, Messina F, Sosa V, Chacón Y, Sosa MLÁ, Mussin J, Cattana ME, Vazquez A, Formosa P, Fernández N, Piedrabuena M, Valdez R, Davalos F, Fernández M, Acuña A, Aguilera A, Guelfand L, Afeltra J, Garcia Effron G, Posse G, Amigot S, Serrano J, Sellares O, Álvarez C, Pineda G, Carnovale S, Zalazar L, Canteros C.J Clinical and Demographic Features of Paracoccidioidomycosis in Argentina: A Multicenter Study Analysis of 466 Cases. Fungi (Basel). 2023 Apr 17;9(4):482. doi: 10.3390/jof9040482.
Cuzziol Boccioni AP, García-Effron G, Peltzer PM, Lajmanovich RC. Effect of glyphosate and ciprofloxacin exposure on enteric bacteria of tadpoles. Rev Argent Microbiol. 2023 Apr-Jun;55(2):120-128. doi: 10.1016/j.ram.2022.08.004.
Landolt NY, Chiani YT, Pujato N, Jacob P, Schmeling MF, García Effron G, Vanasco NB. Utility evaluation of two molecular methods for Leptospira spp. typing in human serum samples. Heliyon. 2022 Dec 25;9(2):e12564. doi: 10.1016/j.heliyon.2022.e12564.
2022
Córdoba S, Abiega C, Agorio I, Amigot S, Ardizzoli K, Giusiano G, Guelfand L, López Moral L, Maldonado I, Pineda G, Garcia-Effron G; Subcomisión de Micología Clínica. Usefulness of the Sensititre YeastOne® panel to detect Candida species resistant to antifungal drugs. Rev Argent Microbiol. 2022 Jan-Mar;54(1):9-14. doi: 10.1016/j.ram.2021.02.002.
Sasoni N, Hartman MD, García-Effron G, Guerrero SA, Iglesias AA, Arias DG. Functional characterization of monothiol and dithiol glutaredoxins from Leptospira interrogans. Biochimie. 2022 Jun;197:144-159. doi: 10.1016/j.biochi.2022.02.006.
Ceballos-Garzon A, Garcia-Effron G, Cordoba S, Rodriguez JY, Alvarez-Moreno C, Pape PL, Parra-Giraldo CM, Morales-López S. Head-to-head comparison of CLSI, EUCAST, Etest and VITEK®2 results for Candida auris susceptibility testing. Int J Antimicrob Agents. 2022 Apr;59(4):106558. doi: 10.1016/j.ijantimicag.2022.106558
Giusiano G, Fernández NB, Vitale RG, Alvarez C, Ochiuzzi ME, Santiso G, Cabeza MS, Tracogna F, Farías L, Afeltra J, Noblega LM, Giuliano CV, Garcia-Effron G. Usefulness of Sōna Aspergillus Galactomannan LFA with digital readout as diagnostic and as screening tool of COVID-19 associated pulmonary aspergillosis in critically ill patients. Data from a multicenter prospective study performed in Argentina. Med Mycol. 2022 May 18;60(5):myac026. doi: 10.1093/mmy/myac026.
Sasoni N, Maidana M, Latorre-Rapela MG, Morales-Lopez S, Berrio I, Gamarra S, Garcia-Effron G. Candida auris and some Candida parapsilosis strains exhibit similar characteristics on CHROMagarTMCandida Plus. Med Mycol. 2022 Oct 8:myac062. doi: 10.1093/mmy/myac062.
Cabeza MS, Gómez A, Sasoni N, Gamarra S, Garcia-Effron G. Black grain eumycetoma due to Diaporthe ueckerae. Taxonomical update of previous agents of infections due to Diaporthe spp. Med Mycol Case Rep. 2022 Dec 1;39:1-4. doi: 10.1016/j.mmcr.2022.11.001.
2021
Morales-Lopez S, Garcia-Effron G. Infections due to rare Cryptococcus species. A literature review”. J Fungi (Basel). 2021 Apr 7;7(4):279.
Garcia-Effron G. Molecular markers of antifungal resistance: potential uses in routine practice and future perspectives. J Fungi (Basel). 2021 Mar 9;7(3):197.
Córdoba S, Abiega C, Agorio I, Amigot S, Ardizzoli K, Giusiano G, Guelfand L, López Moral L, Maldonado I, Pineda G, Garcia-Effron G; Subcomisión de Micología Clínica. Usefulness of the Sensititre YeastOne® panel to detect Candida species resistant to antifungal drugs. Rev Argent Microbiol. 2021 Apr 16: S0325-7541(21)00035-3.
Macedo D, Leonardelli F, Gamarra S, Garcia-Effron G. Emergence of triazole resistance in Aspergillus spp. in Latin America. 2021. Current Fungal Infections Reports. May 19:1-11.
Chen SC, Perfect J, Colombo AL, Cornely OA, Groll AH, Seidel D, Albus K, de Almedia JN Jr, Garcia-Effron G, Gilroy N, Lass-Flörl C, Ostrosky-Zeichner L, Pagano L, Papp T, Rautemaa-Richardson R, Salmanton-García J, Spec A, Steinmann J, Arikan-Akdagli S, Arenz DE, Sprute R, Duran-Graeff L, Freiberger T, Girmenia C, Harris M, Kanj SS, Roudbary M, Lortholary O, Meletiadis J, Segal E, Tuon FF, Wiederhold N, Bicanic T, Chander J, Chen YC, Hsueh PR, Ip M, Munoz P, Spriet I, Temfack E, Thompson L, Tortorano AM, Velegraki A, Govender NP. Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. Lancet Infect Dis. 2021 Aug 19: S1473-3099(21)00203-6.
Espinel-Ingroff A, Sasso M, Turnidge J, Arendrup M, Botterel F, Bourgeois N, Bouteille B, Canton E, Cassaing S, Dannaoui E, Dehais M, Delhaes L, Dupont D, Fekkar A, Fuller J, Garcia-Effron G, Garcia J, Gonzalez GM, Govender NP, Guegan H, Guinea J, Houzé S, Lass-Flörl C, Pelaez T, Forastiero A, Lackner M, Magobo R. Etest ECVs/ECOFFs for detection of resistance in prevalent and three non-prevalent Candida spp. to triazoles and amphotericin B and Aspergillus spp. to caspofungin: Further assessment of modal variability. Antimicrob Agents Chemother. 2021 Aug 9:AAC0109321.
Macedo D, Leonardelli F, Cabeza M, Gamarra S, Garcia-Effron G. The natural occurring Y129F polymorphism in Rhizopus oryzae (R. arrhizus) Cyp51Ap accounts for its intrinsic Voriconazole Resistance. Medical Mycology. 2021. Sep 22;myab052.
2020
Chaves MS, Leonardelli F, Franco DM, Ríos PG, Colli GM, Gutiérrez AR, Ferri M, Elgadban MC, Basaldúa ML, Boleas M, Feltes-Silva P, Bantar C, Gamarra S, García-Effrón G. Control of an outbreak of post-transplant cutaneous mucormycosis by removing the vehicle: An intervention study of contiguous cohorts. Am J Infect Control. 2020 Jul;48(7):791-794.
Macedo D, Brito Devoto T, Pola S, Finquelievich JL, Cuestas ML, Garcia-Effron G. A Novel Combination of CYP51A Mutations Confers Pan-Azole Resistance in Aspergillus fumigatus. Antimicrob Agents Chemother. 2020 Jul 22;64(8): e02501-19.
Editor´s pick.
Brito Devoto T, Hermida-Alva K, Posse G, Finquelievich JL, García-Effrón G, Cuestas ML. High prevalence of triazole-resistant Aspergillus fumigatus sensu stricto in an Argentinean cohort of patients with cystic fibrosis. Mycoses. 2020 Sep;63(9):937-941.
Garcia-Effron G. Rezafungin-Mechanisms of Action, Susceptibility and Resistance: Similarities and Differences with the Other Echinocandins. J Fungi (Basel). 2020 Nov 1;6(4):262.
Sasoni N, Rodriguez Müller M, Posse G, González J, Leonardelli F, Garcia-Effron G. SARS-CoV-2 and Aspergillus section Fumigati coinfection in an immunocompetent patient treated with corticosteroids. Rev Iberoam Micol. 2020 Nov 28: S1130-1406(20)30054-1.
2019
Dudiuk C, Berrio I, Leonardelli F, Morales-Lopez S, Theill L, Macedo D, Yesid-Rodriguez J, Salcedo S, Marin A, Gamarra S, Garcia-Effron G. Antifungal activity and killing kinetics of anidulafungin, caspofungin and amphotericin B against Candida auris. J Antimicrob Chemother. 2019 May 12.
Leonardelli F, Macedo D, Dudiuk C, Theill L, Cabeza MS, Gamarra S, Garcia-Effron G. In Vitro Activity of Combinations of Zinc Chelators with Amphotericin B and Posaconazole against Six Mucorales Species. Antimicrob Agents Chemother. 2019 Apr 25;63(5).
Macedo D, Leonardelli F, Dudiuk C, Vitale RG, Del Valle E, Giusiano G, Gamarra S, Garcia-Effron G. In Vitro and In Vivo Evaluation of Voriconazole-Containing Antifungal Combinations against Mucorales Using a Galleria mellonella Model of Mucormycosis. J Fungi (Basel). 2019 Jan 8;5(1).
Espinel-Ingroff A, Turnidge J, Alastruey-Izquierdo A, Botterel F, Canton E, Castro C, Chen YC, Chen Y, Chryssanthou E, Dannaoui E, Garcia-Effron G, Gonzalez GM, Govender NP, Guinea J, Kidd S, Lackner M, Lass-Flörl C, Linares-Sicilia MJ, López-Soria L, Magobo R, Pelaez T, Quindós G, Rodriguez-Iglesia MA, Ruiz MA, Sánchez-Reus F, Sanguinetti M, Shields R, Szweda P, Tortorano A, Wengenack NL, Bramati S, Cavanna C, DeLuca C, Gelmi M, Grancini A, Lombardi G, Meletiadis J, Negri CE, Passera M, Peman J, Prigitano A, Sala E, Tejada M. Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Methods. Antimicrob Agents Chemother. 2018 Dec 21;63(1).
2018
Gamarra S, Chaves MS, Cabeza MS, Macedo D, Leonardelli F, Franco D, Boleas M, Garcia-Effron G. Mucormycosis outbreak due to Rhizopus microsporus after arthroscopic anterior cruciate ligament reconstruction surgery evaluated by RAPD and MALDI-TOF Mass spectrometry. J Mycol Med. 2018 Dec;28(4):617-622.
Isla G, Leonardelli F, Tiraboschi IN, Refojo N, Hevia A, Vivot W, Szusz W, Córdoba SB, García-Effron G. First Clinical Isolation of an Azole-Resistant Aspergillus fumigatus Isolate Harboring a TR46 Y121F T289A Mutation in South America. Antimicrob Agents Chemother. 2018 Sep 24;62(10).
Macedo D, Leonardelli F, Dudiuk C, Theill L, Cabeza MS, Gamarra S, Garcia-Effron G. Molecular Confirmation of the Linkage between the Rhizopus oryzae CYP51A Gene Coding Region and Its Intrinsic Voriconazole and Fluconazole Resistance. Antimicrob Agents Chemother. 2018 Jul 27;62(8).
Theill L, Dudiuk C, Morales-Lopez S, Berrio I, Rodríguez JY, Marin A, Gamarra S, Garcia-Effron G. Single-tube classical PCR for Candida auris and Candida haemulonii identification. Rev Iberoam Micol. 2018 Apr - Jun;35(2):110-112.
Espinel-Ingroff A, Turnidge J, Alastruey-Izquierdo A, Dannaoui E, Garcia-Effron G, Guinea J, Kidd S, Pelaez T, Sanguinetti M, Meletiadis J, Botterel F, Bustamante B, Chen YC, Chakrabarti A, Chowdhary A, Chryssanthou E, Córdoba S, Gonzalez GM, Guarro J, Johnson EM, Kus JV, Lass-Flörl C, Linares-Sicilia MJ, Martín-Mazuelos E, Negri CE, Pfaller MA, Tortorano AM. Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of cyp51A Mutations on Estimation of Epidemiological Cutoff Values. Antimicrob Agents Chemother. 2018 Mar 27;62(4).
2017
Cattana ME, Dudiuk C, Fernández M, Rojas F, Alegre L, Córdoba S, Garcia-Effron G, Giusiano G. Identification of Candida parapsilosis Sensu Lato in Pediatric Patients and Antifungal Susceptibility Testing. Antimicrob Agents Chemother. 2017 Jun 27;61(7).
Morales-López S, Dudiuk C, Vivot W, Szusz W, Córdoba SB, Garcia-Effron G. Phenotypic and Molecular Evaluation of Echinocandin Susceptibility of Candida glabrata, Candida bracarensis, and Candida nivariensis Strains Isolated during 30 Years in Argentina. Antimicrob Agents Chemother. 2017 Jun 27;61(7).
Dudiuk C, Macedo D, Leonardelli F, Theill L, Cabeza MS, Gamarra S, Garcia-Effron G. Molecular Confirmation of the Relationship between Candida guilliermondii Fks1p Naturally Occurring Amino Acid Substitutions and Its Intrinsic Reduced Echinocandin Susceptibility. Antimicrob Agents Chemother. 2017 Apr 24;61(5).
Leonardelli F, Theill L, Nardin ME, Macedo D, Dudiuk C, Mendez E, Gamarra S, Garcia-Effron G. First itraconazole resistant Aspergillus fumigatus clinical isolate harbouring a G54E substitution in Cyp51Ap in South America. Rev Iberoam Micol. 2017 Jan - Mar;34(1):46-48.
Dudiuk C, Morales-López SE, Podesta V, Macedo D, Leonardelli F, Vitale RG, Tosello ME, Cabeza MS, Biasoli M, Gamarra S, Garcia-Effron G. Multiplex PCR designed to differentiate species within the Candida glabrata complex. Rev Iberoam Micol. 2017 Jan - Mar;34(1):43-45.
2016
Espinel-Ingroff A, Arendrup M, Cantón E, Cordoba S, Dannaoui E, García-Rodríguez J, Gonzalez GM, Govender NP, Martin-Mazuelos E, Lackner M, Lass-Flörl C, Linares Sicilia MJ, Rodriguez-Iglesias MA, Pelaez T, Shields RK, Garcia-Effron G, Guinea J, Sanguinetti M, Turnidge J. Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method. Antimicrob Agents Chemother. 2016 Dec 27;61(1).
Morales-López SE, Taverna CG, Bosco-Borgeat ME, Maldonado I, Vivot W, Szusz W, Garcia-Effron G, Córdoba SB. Candida glabrata species complex prevalence and antifungal susceptibility testing in a culture collection: First description of Candida nivariensis in Argentina. Mycopathologia. 2016 Dec;181(11-12):871-878.
Chaves MS, Franco D, Nanni JC, Basaldúa ML, Boleas M, Aphalo G, Feltes Silva P, Elgadban MC, Emery F, Gamarra S, Garcia-Effron G, Bantar C. Control of an outbreak of postoperative bone mucormycosis: An intervention study of contiguous cohorts. Am J Infect Control. 2016 Dec 1;44(12):1715-1717.
Leonardelli F, Macedo D, Dudiuk C, Cabeza MS, Gamarra S, Garcia-Effron G. Aspergillus fumigatus Intrinsic Fluconazole Resistance Is Due to the Naturally Occurring T301I Substitution in Cyp51Ap. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5420-6.
Theill L, Dudiuk C, Morano S, Gamarra S, Nardin ME, Méndez E, Garcia-Effron G. Prevalence and antifungal susceptibility of Candida albicans and its related species Candida dubliniensis and Candida africana isolated from vulvovaginal samples in a hospital of Argentina. Rev Argent Microbiol. 2016 Jan-Mar;48(1):43-9.
2015
Espinel-Ingroff A, Alvarez-Fernandez M, Cantón E, Carver PL, Chen SC, Eschenauer G, Getsinger DL, Gonzalez GM, Govender NP, Grancini A, Hanson KE, Kidd SE, Klinker K, Kubin CJ, Kus JV, Lockhart SR, Meletiadis J, Morris AJ, Pelaez T, Quindós G, Rodriguez-Iglesias M, Sánchez-Reus F, Shoham S, Wengenack NL, Borrell Solé N, Echeverria J, Esperalba J, Gómez-G de la Pedrosa E, García García I, Linares MJ, Marco F, Merino P, Pemán J, Pérez Del Molino L, Roselló Mayans E, Rubio Calvo C, Ruiz Pérez de Pipaon M, Yagüe G, Garcia-Effron G, Guinea J, Perlin DS, Sanguinetti M, Shields R, Turnidge J. Multicenter study of epidemiological cutoff values and detection of resistance in Candida spp. to anidulafungin, caspofungin, and micafungin using the Sensititre YeastOne colorimetric method. Antimicrob Agents Chemother. 2015 Nov;59(11):6725-32.
Dudiuk C, Gamarra S, Jimenez-Ortigosa C, Leonardelli F, Macedo D, Perlin DS, Garcia-Effron G. Quick Detection of FKS1 Mutations Responsible for Clinical Echinocandin Resistance in Candida albicans. J Clin Microbiol. 2015 Jul;53(7):2037-41.
Gamarra S, Mancilla E, Dudiuk C, Garcia-Effron G. Candida dubliniensis and Candida albicans differentiation by colony morphotype in Sabouraud-triphenyltetrazolium agar. Rev Iberoam Micol. 2015 Apr-Jun;32(2):126-8.
2014
Gamarra S, Morano S, Dudiuk C, Mancilla E, Nardin ME, de Los Angeles Méndez E, Garcia-Effron G. 2014. Epidemiology and antifungal susceptibilities of yeasts causing vulvovaginitis in a teaching hospital. Mycopathologia. Epub ahead of print Jul 9.
Dudiuk C, Gamarra S, Leonardeli F, Jimenez-Ortigosa C, Vitale RG, Afeltra J, Perlin DS, Garcia-Effron G. 2014. Set of Classical PCRs for detection of mutations in Candida glabrata FKS genes linked with echinocandin resistance. J Clin Microbiol. Jul; 52(7): 2609-14.
2013
Datta K, Rhee P, Byrnes E 3rd, Garcia-Effron G, Perlin DS, Staab JF, Marr KA. 2013. Isavuconazole activity against emerging fungal pathogens with reduced azole-susceptibility: Aspergillus lentulus, Neosartorya udagawae and Cryptococcus gattii. J Clin Microbiol. 2013 Sep; 51 (9): 3090-93.
Gamarra S, Dudiuk C, Mancilla E, Vera Garate MV, Guerrero S, Garcia-Effron G. 2013. Molecular tolos for cryptic Candida species identification with applications in a clinical laboratory. Biochem Mol Biol Educ. May-Jun; 41(3):180-6.
2012
García-Effron G, Canton E, Pemán J, Dilger A, Romá E, Perlin DS. 2012. Epidemiology and echinocandin susceptibility of Candida parapsilosis sensu lato species isolated from blood stream infections at a Spanish University Hospital. Journal of Antimicrobial Chemotherapy. Nov; 67(11):2739-48.
Pratt A, Garcia-Effron G, Zhao Y, Park S, Mustaev A, Pillai S, Perlin DS. 2012. Evaluation of fungal-specific fluorescent labeled echinocandin probes as diagnostic adjuncts. Med. Mycol. Jan; 51(1): 103-7.
2011
Bartoli MZ, Cingolani B, García-Effron G, Gamarra S. 2011. Análisis de métodos fenotípicos para la diferenciación de Candida dubliniensis y Candida albicans. Propuesta de una secuencia de identificación. Revista FABICIB. 2011. 15: 138-149.
García-Effron G, Canton E, Pemán J, Dilger A, Romá E, Perlin DS. 2011. Assessment of two new molecular based methods for identification of Candida parapsilosis sensu lato species. 2011. Journal of Clinical Microbiology. 49(9):3257-61. PMID: 21795509.
Ben-Ami R, Garcia-Effron G, Lewis RE, Gamarra S, Leventakos K, Perlin DS, Kontoyiannis DP. 2011. Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance. J. Infect. Dis. 204 (4): 626-35. PMID: 21791665.
García-Effron G, Park S, Perlin DS. Improved detection of Candida spp. fks hot spot mutants using the CLSI M27-A3 document by the addition of Bovine Serum Albumin (BSA). Antimicrob Agents Chemother. 2011. 55(5):2245-55. PMID: 21383097.
Arendrup M, Rodriguez-Tudela JL, Park S, García-Effron G, Delmas G, Cuenca-Estrella M, Gomez-Lopez A, Perlin DS. Echinocandin susceptibility testing of Candida spp. using the EUCAST EDef 7.1 and CLSI M27-A3 standard procedures: Analysis of the influence of Bovine Serum Albumin Suplementation, Storage Time and Drug Lots. Antimicrob Agents Chemother. 2011. 55(4):1580-7. PMID: 21245440.
Gamarra S y García-Effron G. Evolución de la producción científica de Argentina en microbiología entre los años 1987 y 2009. Revista FABICIB. 2011. 14: 209-223.
2010
Zhang YQ, Gamarra S, García-Effron G, Park S, Perlin DS, Rao R. Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs. PLoS Pathog. 2010. Jun 3; 6(6): e1000939. PMID: 20532216.
Rodriguez-Tudela JL, Gomez-Lopez A, Arendrup MC, García-Effron G, Perlin DS, Lass-Flörl C, Cuenca-Estrella M. Comparison of Caspofungin MICs by means of EUCAST EDef 7.1 using two different concentrations of glucose. Antimicrob Agents Chemother. 2010. Jul; 54(7): 3056-7. PMID; 20479199.
Pfeiffer CD, García-Effron G, Zaas AK, Perfect JR, Perlin DS, Alexander BD. Breakthrough Invasive Candidiasis on Micafungin. J Clin Microbiol. 2010. Jul; 48 (7): 2373-80. PMID: 20421445.
García-Effron G, Chua DJ, Tomada JR, Dipersio J, Perlin DS, Ghannoum M, Bonilla H. Novel FKS Mutations Associated with Echinocandin Resistance in Candida Species. Antimicrob Agents Chemother. 2010. May; 54(5):2225-7. PMID: 20145084.
Gamarra S, Rocha EM, Zhang YQ, Park S, Rao R, Perlin DS. Mechanism of the synergistic effect of amiodarone and fluconazole in Candida albicans. Antimicrob Agents Chemother. 2010 May;54(5):1753-61. Epub 2010 Mar 1.PMID: 20194694.
Martínez-López J, Crooke A, Grande S, Ayala R, Jiménez-Velasco A, Gamarra S, Meneu JC, Gilsanz F. Real-time PCR quantification of haematopoietic chimerism after transplantation: a comparison between TaqMan and hybridization probes technologies. Int J Lab Hematol. 2010 Feb;32(1 Pt 1):e17-25. Epub 2009 May 12. PMID: 19453606.
Arendrup MC, García-Effron G, Lass-Flörl C, Lopez AG, Rodriguez-Tudela JL, Cuenca-Estrella M, Perlin DS. Echinocandin Susceptibility Testing of Candida species: Comparison of EUCAST EDef 7.1, CLSI M27-A3, Etest, Disk Diffusion, and Agar Dilution Methods with RPMI and Isosentistest Media. Antimicrob Agents Chemother. 2010. Jan; 54(1):426-39. PMID: 19884370.
2009
Gamarra S, García-Effron G, Monteserin C, Lopez-Villar I, Gilsanz F, Martinez-Lopez J. 2009. β-ThalassaemiaMajor in a Spanish Patient due to a Compound Heterozygosity for CD39 C → T/−28 A → C. Advances in Hematology. 2009: 476342. PMID: 19960060.
García-Effron G, Lee S, Park S, Cleary JD, Perlin DS. Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-b-D-glucan synthase: implication for the existing susceptibility breakpoint. Antimicrob Agents Chemother. 2009. Sep; 53(9):3690-9. PMID: 19546367.
Arendrup MC, García-Effron G, Buzina W, Mortensen KL, Reiter N, Lundin C, Jensen HE, Lass-Flörl C, Perlin DS, Bruun B. BreakthroughAspergillus fumigatus and Candida albicans double infection during caspofungin treatment: laboratory characteristics and implication for susceptibility testing. Antimicrob Agents Chemother. 2009. Mar; 53(3): 1185-93.PMID: 19104024.
García-Effron G, Park S, Perlin DS. Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans: Implications for Interpretive Breakpoints. Antimicrob Agents Chemother. 2009. Jan; 53 (1): 112-22. PMID: 18955538.
2008
García-Effron G, Kontoyiannis DP, Lewis RE, Perlin DS. Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic malignancies. Antimicrob Agents Chemother. 2008 Nov; 52(11): 4181-3. PMID: 18794386.
Wiederhold NP, Grabinski JL, García-Effron G, Perlin DS, Lee SA.Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans. Antimicrob Agents Chemother. 2008 Nov; 52(11): 4145-8. PMID: 18794385.
Arendrup MC, Perkhofer S, Howard AJ, García-Effron G, Kumar V, Perlin DS, Latgè JP, Lass-Flörl C. Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins. Antimicrob Agents Chemother. 2008 Oct;52(10):3504-11. PMID: 18644959.
García-Effron G, Katiyar S, Park S, Edlind TD, Perlin DS. A naturally ocurring Proline-to-Alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis and Candida metapsilosis accounts for reduced echinocandin susceptibility. Antimicrob Agents Chemother. 2008 Jul; 52(7): 2305-12. PMID: 1844311.
Cleary JD, García-Effron G, Chapman SW, Perlin DS. Caspofungin resistance in Candida glabrata secondary to a FKS1 mutation developed during candidemia treatment. Antimicrob Agents Chemother. 2008 Jun; 52 (6): 2263-5. PMID: 18378714.
García-Effron G, Dilger A, Alcazar-Fuoli L, Park S, Mellado E, Perlin DS. Rapid detection of triazole antifungal resistance in Aspergillus fumigatus. Journal of Clinical Microbiology. 2008 Apr; 46 (4): 1200-6. PMID: 18234874.
2007
Alcazar-Fuoli L, Mellado E, García-Effron G, Lopez JF, Grimalt JO, Cuenca-Estrella JM, Rodriguez-Tudela JL. Ergosterol biosynthesis pathway in Aspergillus fumigatus. Steroids. 2007 73 (3): 339-347. PMID: 18191972.
Rocha EM, García-Effron G, Park S, Perlin DS. A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus. Antimicrob Agents Chemother. 2007. 51(11):4174-6. PMID: 17724146.
García-Effron G, Gamarra S, Crooke Alvarez A, Martinez-Sanchez P, Lahuerta-Palacios J, Martinez-Lopez J. Comparison of the MagNA Pure LC Automated System and the Ribo Pure – Blood RNA Manual Method for RNA Extraction from Multiple Myeloma Bone Marrow Samples Conserved in an RNA stabilizer. Int. J. Lab. Hematol. 2007. 29: 139–144. PMID: 17474887.
Paderu P, García-Effron G, Balashov S, Delmas G, Park S, Perlin DS. Serum differentially alters the antifungal properties of echinocandin drugs. Antimicrob Agents Chemother. 2007. 51(6): 2253-6. PMID: 17420211.
Mellado E, García-Effron G, Alcazar-Fuoli L, Melchers WJ, Verweij PE, Cuenca-Estrella M, Rodriguez-Tudela JL. A new Aspergillus fumigatusresistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations. Antimicrob Agents Chemother. 2007. 51(6): 1897-904. PMID: 17371828.
Kahn JN, García-Effron G, Hsu MJ, Park S, Marr KA, Perlin DS. Acquired echinocandin resistance in a Candida krusei isolate due to modification of glucan synthase. Antimicrob Agents Chemother. 2007. 51(5): 1876-8. PMID: 17325225.
2006
Mellado E, Alcazar-Fuoli L, García-Effron G, Alastruey-Izquierdo A, Cuenca-Estrella M, Rodríguez-Tudela JL. New resistance mechanisms to azole drugs in Aspergillus fumigatus and emergence of antifungal drugs-resistant A. fumigatus atypical strains. Medical Mycology. 2006. 44 Suppl:367-71.
Quintela-Fandino M, Hitt R, Medina PP, Gamarra S, Manso L, Cortes-Funes H, Sanchez-Cespedes M. DNA-repair gene polymorphisms predict favorable clinical outcome among patients with advanced squamous cell carcinoma of the head and neck treated with cisplatin-based induction chemotherapy. J. Clin. Oncol. 2006. 24 (26): 4333-9. PMID: 16896002.
Martinez-Lopez J, Martinez-Sanchez P, García-Sanz R, Sarasquete ME, Ayala R, Gonzalez M, Bautista JM, Gonzalez D, San Miguel J, García-Effron G, Lahuerta JJ. Application of self-quenched JH consensus primers for real-time quantitative PCR of IgH gene to minimal residual disease evaluation in multiple myeloma. Journal of Molecular Diagnostics. 2006. 8(3):364-70. PMID: 16825510.
Quintela-Fandino M, López JM, Hitt R, Gamarra S, Jimeno A, Ayala R, Hornedo J, Guzman C, Gilsanz F, Cortés-Funes H. Breast cancer-specific mRNA transcripts presence in peripheral blood after adjuvant chemotherapy predicts poor survival among high-risk breast cancer patients treated with high-dose chemotherapy with peripheral blood stem cell support. J. Clin. Onclo. 2006. 24 (22):3611-8. PMID: 16877728.
Cuenca-Estrella M, Gomez-Lopez A, Buitrago MJ, Mellado E, García-Effron G, Rodriguez-Tudela JL. In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis. Antimicrob Agents Chemother. 2006. 50(6):2248-50. PMID: 16723597.
Alcazar-Fuoli L, Mellado E, García-Effron G, Buitrago MJ, Lopez J, Grimalt J, Cuenca-Estrella M, Rodriguez-Tudela JL. Aspergillus fumigatus C-5 sterol desaturases (Erg3A and Erg3B): role in sterol biosynthesis and antifungal drugs susceptibility. Antimicrob Agents Chemother. 2006. 50(2):453-60. PMID: 16436696.
2005
Cuenca-Estrella M, Gomez-Lopez A, Mellado E, García-Effron G, Monzon A, Rodriguez-Tudela JL. In vitro activity of ravuconazole against 923 clinical isolates of nondermatophyte filamentous fungi. Antimicrob Agents Chemother. 2005. 49(12):5136-8. PMID: 16304186.
Mellado E, García-Effron G, Buitrago MJ, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drugs susceptibility. Antimicrob Agents Chemother. 2005.49(6):2536-8. PMID: 15917566.
García-Effron G, Mellado E, Gomez-Lopez A, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Differences in interactions between azole drugs related to modifications in the 14-alpha Sterol Demethylase Gene (cyp51A) of Aspergillus fumigatus. Antimicrob Agents Chemother. 2005. 49(5):2119-21. PMID: 15855543.
Cuenca-Estrella M, Gomez-Lopez A, García-Effron G, Alcazar L, Mellado E, Buitrago MJ, Rodriguez-Tudela JL. Combined activity in vitro of caspofungin, amphotericin B and azole agents against itraconazole resistant clinical isolates of Aspergillus fumigatus. Antimicrob Agents Chemother. 2005. 49(3):1232-5. PMID: 15728937.
2004
Cuenca-Estrella M, Gomez-Lopez A, Mellado E, García-Effron G, Rodriguez-Tudela JL. In vitro activities of ravuconazole and four other antifungal agents against fluconazole-resistant or -susceptible clinical yeast isolates. Antimicrob Agents Chemother. 2004. 48(8):3107-11. PMID: 15273127.
Mellado E, García-Effron G, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs. Antimicrob Agents Chemother. 2004. 48(7):2747-50. PMID: 15215142.
García-Effron G, Gomez-Lopez A, Mellado E, Monzon A, Rodriguez-Tudela JL, Cuenca-Estrella M. In vitro activity of terbinafine against medically important non-dermatophyte species of filamentous fungi. J Antimicrob Chemother. 2004. 53(6):1086-9. PMID: 15102749.
2003
Gomez-Lopez A, García-Effron G, Mellado E, Monzon A, Rodriguez-Tudela JL, Cuenca-Estrella M. In vitro activities of three licensed antifungal agents against spanish clinical isolates of Aspergillus spp. Antimicrob Agents Chemother. 2003. 47(10):3085-8. PMID: 14506013.
2002
Cuenca-Estrella M, Rodero L, García-Effron G, Rodríguez-Tudela J.Antifungal susceptibilities of Candida spp. Isolated from blood in Spain and Argentina, 1996 – 1999. Journal of Antimicrobial Chemotherapy. 2002. 49: 981 – 987. PMID: 12039890.
Sarsotti P, Hernandez A, Pawluk D, Gutierrez C, García-Effron G, Seba-Ponzoni C. Cyclospora cayetanensis: Un protozoo emergente en expansión. Primer caso en Santa Fe, Argentina. Revista FABICIB. 2002. 6: 153-54.
2001
García-Effron G, Gutierrez C, Sarsotti P, Vanni C. Determinación de la variedad en cepas de Cryptococcus neoformans del cepario de la Cátedra de Micología de la Facultad de Bioquímica y Ciencias Biológicas de la Universidad Nacional del Litoral. Revista FABICIB. 2001. 5: 57-59.
1998
Vanni C, Sarsotti P, Ruatta J, García-Effron G, Gutiérrez C, Cabagna M. Ecología del Cryptococcus neoformans en Santa Fe (Argentina).Revista FABICIB. 1998. 2: 25-30